According to research, anal cancer mortality can now take away 80 percent of a person’s lifespan, specifically gays and bi-sexual. Such findings were determined from an age-specific group of individuals.
In 2014, there are an estimated 620,000 bisexual and gay men from the United States who were infected with HIV. And about 100,000 of them are entirely unaware that they have the said disease. Such men are more prone to have 100 times chances of getting anal cancer compared to men tested negative for HIV. Despite this alarming data, no guidelines were imposed for national screening to check people for anal cancer.
Anal cancer can be the result of a continuous human papillomavirus (HPV) infection. Such infection, when not addressed at an early stage, can lead to anal precancer or even anal cancer. It was also revealed that such disease is also the culprit of rectal cancers, penile, oropharyngeal, vulvar, vaginal and even cervical cancers.
Because of these facts, screenings are being encouraged to point out patients and treat this health condition at the earliest stage possible. However, such advocate couldn’t be pushed through up until this moment, because treatment for this disease is still not yet discovered. That is why such study is now being made known to the public through the Cancer journal to encourage medical professionals to find a remedy to help the infected gay and bisexual who are HIV positive to get away from cancer.
Anal Cancer: The Next Big Crisis
Medical professionals stated that anal cancer is said to be the next crisis for people infected with HIV. During the 1990s, anti-retroviral therapy was found to be a massive help for AIDS-infected patients since it was able to reduce the death rate amongst patients and even improve their survival rates. However, on the other side, such improvement also increases the chances of anal cancer on bisexual and gay who were tested HIV positive.
One out of two American men is said to be infected with HPV. HPV infection is the root of anal precancer and which will eventually lead to anal cancer if such ailment remained undetected and untreated. Fact is in 2017; there are 8200 new anal cases identified by the American Cancer Society. And it was assumed that if national screening is still not available, fifty percent of these cases will elevate to Stage 3 and Stage 4 over time. And in such cases, there is only 40 percent chance of surviving within five years. No treatment discovered or management routine was yet created for such disease. And up to this point, research is being conducted to address anal cancer in the best possible way.
How Our Study Brings Insight
With the use of a mathematical model, we assume that life course of about 100000 HIV positive who has experience with same-sex intercourse and are 27 years old and older. And these individuals were tested to have this high-grade intraepithelial condition. We then compare the data according to four management styles namely:
- patients not provided with any treatment
- patients who have early cancer and are monitored
- patients treated through surgery
- patients who undergone surgery also got HPV vaccination
These categorized patients were monitored to identify the advantages and disadvantage of the recognized management styles. These individuals are tracked, included also are the individuals whose condition advanced to cancer. Death risk was estimated based on the findings. The patient’s age categorized results. And for each management style, age-specific lifetime results, life expectancy, and life quality were estimated.
It was then uncovered that people with HIV infection, with age 38 years old and older must be treated with the use of the surgical procedure. This can be done either by infrared coagulation or the electrocautery and at the time of surgery, HPV vaccination must be given to the patient. The idea is found to be less costly and has excellent chances of decreasing anal cancer lifetime risk up to 80 percent.
According to the model also, younger men have higher chances of overcoming the precancer stage even without any medical intervention. These patients are 29 years old and below. Patients aging between 29 to 38 years old should be monitored all the time to get away from the possible treatment inconvenience and mortality which can directly affect their quality of life.
How The HPV Vaccine Could Help
At present, HPV vaccination is not advisable for people aging 27 years old and older. However, according to findings, people with HPV vaccine that are in their precancer stage have lesser chances of coming back for other rounds of treatment.
HPV vaccines are found to have lesser effects that are why medical professionals are considering the idea. And the most significant advantage of such is the smaller number of treatments for the patient. And post-treatment HPV vaccine can also help lessen the anal cancer lifetime risk.
(Note: This disease is very serious. If you, a family member or close friend has the ailment, then, you might want to consider the information provided above. You might also benefit from therapy or counseling.)